The region saw just over 5,000 acres consumed by urban growth in six years, according to a the survey, which shows the loss of an area almost the size of the Quantock Hills or Windsor Great Park, in the outskirts of London.
Almost 4.5% of the arable land in Devon, Cornwall and Somerset saw was turned into bricks and mortar between 2006 and 2012, the new map shows.
This represents around a seventh of the 35,000 acres of agricultural land lost to the spread of towns and cities across the whole UK.